Renal Cortical Necrosis: An Unusual Complication of Plasmodium malariae Malaria.
Renal cortical necrosis (RCN) is anecdotal in malaria. To our knowledge, RCN secondary to Plasmodium
malariae has not yet been published. We report a case of severe malaria complicated by
RCN. A 29 year old Senegalese patient was transferred to our department for anuria in a context of
severe malaria. The diagnosis was RCN secondary to a severe Plasmodium malariae malaria.
Physical examination showed anuria, anaemic syndrome, haemorrhagic syndrome and a generally
impaired condition. There was a normocytic normochromic anaemia aplastic, thrombocytopenia
leukocytosis of 11.580/mm3, serum creatinine of 12.45 mg/dl and blood urea of 252 mg/dl. The
Plasmodium malariae had been shown to thick blood film with high parasite density. The molecular
study was able to confirm the infestation of this parasite. Treatment consisted of four haemodialysis
sessions and antimalarial molecules. Initial evolution was favourable with a recovery
through diuresis and a partial improvement in renal function. Given the persistence of impaired
renal function, a renal biopsy was performed. This confirmed the RCN. At last consultation, he had
no symptoms and his last glomerular filtration rate (GFR) was 30 mL/min/1.73 m2.
Auteur(s) : Lemrabott AT, Cissé MM, Seck SM, Ka EF, Faye M, Ndongo A, Dial C, KeitaY, Fall K, Niang A, Diouf B.
Pages : 99- 104
Année de publication : 2015
Revue : Open J Nephrol
N° de volume : 5
Type : Article
Statut Editorial : article original
Mise en ligne par : KA El Hadji Fary