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Behcet's disease in black skin. A retrospective study of 50 cases in Dakar

Introduction: AlthoughBehçet'sdiseaseiswell-documentedinEasternpopulations, epidemiologic data in sub Saharan African population is scarce. The aim of this stu- dy was to define the epidemiologic and therapeutic aspects as well as clinical course of Behçet’s disease in African black population. Results: The study included 50 patients with Behçet's disease. The average age was 32(18-67)years.Atotalof31patientsweremenand19werewomen.Twopatients had a positive family history of Behçet’s disease. The oral and genital aphthous le- sionswerepresentin100%ofpatients.Thepathergytestwaspositivein16patients (32%). Following skin conditions were observed: pseudofolliculitis in 15 patients (30%), acneiform papules in 6 patients (12%), erythema nodosum in 4 patients (8%) and leg ulcers in one patient. Ocular involvement was reported in 22 patients (44%) and joint involvement in 20 patients (40%). Neurological abnormalities were noted in 12 patients (24%). Gastrointestinal involvement with wide and deep ulcerations intheileocecalregionwasobservedinapatient.Astreatment,acombinationoforal corticosteroids and colchicine was used in 97% of our patients. Thalidomide was in- troduced in 3 patients and anticoagulation treatment in 19 patients. Clinical impro- vement was noted in 25 patients (50%), recurrence in 14 patients (28%) and 3 pa- tients were lost to follow (6%). Conclusion: The Behçet's disease is not uncommon in black skin and generally af- fects young adults. Severe aphthous ulcers of the oral cavity and genital area are the most consistent finding.

Auteur(s) : Ndiaye Maodo, Sow Sadikh Aboubacry, Abbaspour Valiollah, Diallo Moussa, Diop Assane, Rachidi Alaoui Amal, Diatta Boubacar Ahy, Ly Fatimata, Niang Suza
Pages : 98 - 102
Année de publication : 2015
Revue : Journal of Dermatological Case Reports
N° de volume : 9
Type : Article
Statut Editorial : Revue Internationale
Mise en ligne par : SOW Aboubacry Sadikh