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Cholesterol side chain triazole analogue via cycloaddition “click”chemistry.

An efficient preparation of a cholesterol analogue possessing a triazole ring is achieved starting from commercially available stigmasterol. The procedure is based on a [3+2] cycloaddition of a cholesterol possessing a side-chain terminal azide with a terminal acetylene.


Auteur(s) : Seck, Insa; Fall, Alioune; Lago, Carmen; Sène, Massène; Gaye, Mohamed; Seck, Matar; Gómez, Generosa; Fall, Yagamare
Pages : 2826-2830
Année de publication : 2015
Revue : Synthesis
N° de volume : 47(18)
Type : Article
Mise en ligne par : GAYE Mohamed Lamine