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Schistosoma hematobium-associated glomerulopathy

Schistosomiasis is the second most devastating tropical parasitic disease worldwide and is responsible for many urological complications. However, glomerular injury is a rare complication mainly described with Schistosoma mansoni. We report a case of membranoproliferative glomerulonephritis (MPGN) associated with Schistosoma hematobium infection in a young Senegalese boy living in a rural area. Clinical presentation was with steroid-resistant with nephrotic syndrome. Renal biopsy showed type 1 MPGN with the presence of S. hematobium eggs surrounded by a gigantocellular granuloma. Despite therapy with antihelminthic and immunosuppressive drugs, evolution was characterized by progression to end-stage renal disease over 1 year. More efforts should be made on the prevention and early detection of schistosomiasis among at-risk populations.

Auteur(s) : S. M. Seck, M. L. Sarr1, M. C. Dial2, E. F. Ka
Pages : 201-203
Année de publication : 2011
Revue : Indian Journal of Nephrology July
N° de volume : / Vol 21 / Issue 3
Type : Article
Mise en ligne par : KA El Hadji Fary