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phEnotypic charactErization of uropathogEnic BactEria isolatEd at fann chnu in dakar

while urinary tract infection are mainly caused by bacteria, their treatement is based on antibiotic . Due to the emer- gence of antibiotic resistance worldwide, it is important to update the epidemiological data on urinary tract infection and to educate prescribers on the role of the laboratory in the essential management of these infections and therefo- re in the fight against resistance. The objective of this stu- dy was to determine the phenotypic characteristics of the uropathogenic bacteria isolated at fann CHNU between January and June 2017. It is a retrospective study carried out at the bacteriology la- boratory of fann CHNU in Dakar. Data related to patients and isolated germs were obtained by consulting laboratory registers and antibiogram sheets During the study period, 327 bacterial strains were listed; their distribution showed great diversity with a clear predo- minance of enterobacteria 222 followed by Staphylococci 61; non-fermentative Gram-negative bacteria only repre- sented 30. Of the 222 Enterobacteriaceae isolated from urine, E. coli and Klebsiella spp were mainly represented. 31% of patients were hospitalized the majority were admit- ted to the Neurology service 49% followed by SMIT servi- ces 26%. The study population was characterized mainly by patients aged between 70 and 80 years. The average age was 51; extremes ranging from 4 months to 90 years. The study showed that urinary tract infection were more common in women with a sex ratio (M / f) of 0.83. 31% of patients had at least one of the symptom of infection of the urinary tract (dysuria, hematuria, prostatitis, burns ...). The study of antibiotic sensitivity has shown that beta-lactams are the most affected with 42% of enterobacteria produ- cing broad-spectrum beta-lactamases (ESBL) and 55% of staphylococci with methicillin resistance. Some strains exhibited resistance to carbapenems while the glycopeptid remained sensitive. This study shows that the emergence of resistance to car- bapenems with ESBL-producing strains is all the more worrying since these strains are of community origin. Keywords: Characterization, Bacteria, uropathogen, resistance, antibiotics


Auteur(s) : NIANG AA, KA R , SARR H, DIOP A, f, DIèYE B, f, BA-DIALLO A, D, DIALLO f, LO S, KA M, DIA- GNE R, DIA ML, CISSé Mf, SOw AI
Année de publication : 2020
Type : Article
Mise en ligne par : DIEYE Baïdy