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Phytochemicals content, screening and antioxidant/pro-oxidant activities of Carapa procera (barks) (Meliaceae)

Total phenolic, ?avonoid and tannin contents together with antioxidant and pro-oxidant activities of Carapa procera were investigated. The antioxidant activity of Carapa procera was evaluated by 1,1-diphenyl-2-picryl- hydrazyl (DPPH) assay, ferric reducing/ antioxidant power (FRAP) method and 2,20 -azino bis(3-ethylbenz- thiazoline-6-sulfonic acid) (ABTS) assay. The study of pro-oxidant activity was based on the power producing of iron ion in the Fenton reaction. The total phenolic content (TPC) of the extract was exhibiting high value of 8.2 mg gallic acid equivalents (GAE)/ g of dried Carapa. The study revealed a low percentage of ?avonoids 0.04% in the extract and 0.24 mg of tannic acid equivalents (TAE)/g of dried Carapa for the tannin content (TC). Proanthocyanidins were less represented among the tannins 6.80% of the extract. The chromatographic ?ngerprints showed the presence of tannins and acid, like (+)-catechin, epicatechin, trans-4-hyroxicinnamic,3,4-dihydro xicinnamic and acid chlorogenic. Carapa procera exhibited high antioxidant activity in the both DPPH and ABTS assays, being 10.45 mg Vitamin C equivalents/g of dried Carapa and 500 mmol Trolox/g of dried Carapa, respectively. The FRAP gave a good result 2.45 mg Vitamin C equivalents /g of dried Carapa. The pro-oxidant activity was 24.25 mg/ml of Carapa extract. The phytochemical screening was the subject of intensive investigations in order to identify the chemical constituents present in medicinal plants, such as Carapa procera and to evaluate their potential biological activities.


Auteur(s) : I. Seck, A. Hosu, C. Cimpoiu, S.F. Ndoye, L.A. Ba, C. Sall, M. Seck
Pages : 369-376.
Année de publication : 2021
Revue : South African Journal of Botany
N° de volume : 137
Type : Article
Mise en ligne par : SECK Matar