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Evolutionary Aspects of Electrocardiographic and Echocardiographic Manifestations in Systemic Lupus Erythematosus: Descriptive Longitudinal Study about 25 Cases in 18-Month Monitoring

Introduction: Systemic lupus erythematosus is a major systemic autoimmune disease of unknown cause. It can affect all organs and especially the heart with different proportions. The aim of this study was to determine the evolving electrocardiographic and echocardiographic features in systemic lupus erythematosus. Methodology: This study was carried out at the cardiology and dermatology Aristide Le Dantec Hospital. This is a descriptive longitudinal study conducted from January 2013 to October 2014. We included SLE patients who had at least two echocardiograms and electrocardiograms performed at least 3 months apart. Anamnestic information, electrocardiographic and echocardiographic features were reported on a pre-established survey form. Data were entered using Epi -info software version 3.5.1. Results: We included 25 patients. It was mentioned a female predominance (88%). The average age of patients was 35.5 years. All patients had dermatological signs of systemic lupus erythematosus. Cardiac events were found on clinical examination in 20% of cases. Sixty four percent (64%) of patients had an abnormal electrocardiogram dominated by left ventricular hypertrophy (24%). During 18 months of follow-up, we noted some electrocardiographic changes in 16% of cases. Ultrasound abnormalities were found in 40% of patients: 8% presented a slight expansion of the OG, a patient had impaired left ventricular function with the presence of a spontaneous contrast intra VG and increased filling pressures. Right ventricular function was impaired in one patient. Other abnormalities were found: 12% of aneurysm of the interatrial septum, 4% of atrial septal defect and 4% of pericardial detachment. Conclusion: Cardiovascular violations are fairly common in SLE patients. A study on a large sample and longterm could better assess cardiovascular complications in SLE patients and how they occurred.

Auteur(s) : Ngaïdé AA, Mbaye A, Ad Kane, Thiam AI, Lèye M, Dioum M, Sarr SA, F Aw, Ka MM, Ndiaye M, Gaye ND, Babaka K, Ndiaye M, Ndao CT, Cissé AF,Kouamé I, Thiom
Année de publication : 2016
Revue : Journal of Clinical & Experimental Cardiology
N° de volume : 7
Type : Article
Mise en ligne par : MBAYE Alassane