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Does the algorithms process of post processing in imaging PET replace liver biopsy to determine the stage of differentiation of cells in hepatocellular carcinoma (HCC)?]

The positron emission tomography (PET) is a tool reference in routine clinical oncology. His applications has concerned the management and therapeutic monitoring, identification and definition of targets for radiotherapy, and quantification. The most frequently radiotracer's used are fluo-deoxyglucose(FDG) and Fluo-choline (18F-choline). In addition to the functional information, PET with algorithms of post treatment could give information on the stage of cell differentiation in HCC. The objective is to determine the stage of cell differentiation in HCC on imaging PET. We have apply the process of imaging post treatment on the image of PET Choline and PET FDG of patient whose stage of cell differentiation is known at histology. The same result as histology were found. The volume of HCC lesions detected using 18F-FDG was slightly better than that using 18F-choline. The capacity of these two radiotracers to detect rate of fixation of HCC depend of the type of lesion. This combination could be a new tool which can substitute the liver biopsy if there are not indicated.


Auteur(s) : O Diop , W Sow-Diop, Elhadj .A.L Bathily , Sahar Houidi, B Ndong , R.S Senghor, Louis A.D.Diouf, Alphonse R Djiboune, Papa M Sy, Gora Mbaye, Mbodj Mam
Pages : pp. 360 à 365]
Année de publication : 2016
Revue : International Journal of Innovative Science, Engineering & Technology,
N° de volume : 3(5
Type : Article
Mise en ligne par : MBAYE Gora