Antioxidant and antiglycation properties of two mango (Mangifera indica L.) cultivars from Senegal
Objective: To evaluate the total phenolic contents, antioxidant and antiglycation activities
of leaves, barks, roots and kernels from two cultivars of Mangifera indica (Anacardiaceae).
Methods: Total phenolic contents were determined by using Folin-Ciocalteu’s method. The
antioxidant activities were assessed by three different protocols including DPPH, oxygen
radical absorbance capacity and iron (II) chelation assays. In addition, in vitro bovine serum
albumin/D-ribose assay was chosen to evaluate the antiglycation properties of the extracts.
Results: All the investigated extracts were found to contain high level of total phenols as
well as potent antioxidant activities. Kernel extracts showed the highest total phenol contents
and DPPH radical scavenging activities whereas higher oxygen radical absorbance capacity
values were observed for leave, root and bark extracts. Besides, extracts from leaves, roots
and barks from both cultivars exhibited potent inhibitory effects against the formation of
advanced glycation end products, with IC50 values lower than the standard positive control
aminoguanidine. Conclusions: The potent antiglycation and antioxidative activities of these
two Mangifera indica cultivars suggest a possible role in targeting aging, diabetic complications
and oxidative stress related diseases.
Auteur(s) : Samba Fama Ndoye, Didier Fraisse, Blandine Akendengué, Mbaye Diaw Dioum, Rokhaya Sylla Gueye, Cheikh Sall, Insa Seck, Catherine Felgines, Matar Seck,
Pages : 137-141
Année de publication : 2018
Revue : Asian Pacific Journal of Tropical Biomedicine
N° de volume : 8(3):
Type : Article
Mise en ligne par : SECK Matar