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Cytochrome b and Béta-fibrinogene implication in the genetic evolution of breast malignant tumour in Senegalese women.

The International Cancer Centre (CIRC) stated that there is an important increase of breast cancer throughout the world. In Senegal, breast cancer is known as the malicious tumour more developed among women. From thirty (30) Senegalese women were tested, the notice is that a mitochondrial (Cytochrome b) and a nuclear (Beta-fibrinogen) gene evaluated the level of genetic diversity, genetic differentiation and demographic evolution. Our results showed a real diversity of Cytochrome b compared to Beta-fibrinogen. A significant difference has been found between normal tissues and cancerous ones within Cytochrome b. these results showed an implication of mitochondrial DNA compared to nuclear DNA.


Auteur(s) : Mze A.M., Mbaye F., Kénémé B., Sembène M.
Pages : 503-509
Année de publication : 2017
Revue : International Journal of Advanced Research.
N° de volume : 5 (7)
Type : Article
Mise en ligne par : SEMBENE Mbacké