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Colorectal Cancers in Mauritania: Clinical Aspects and Treatment

The aim of our study was to determine epidemiological, clinical and therapeutic pro- file of colorectal cancers in Mauritania. Patients and Methods: It was a retrospective multicentric study conducted over 5 years in Nouakchott National Hospital Centre and in private clinics of Mauritania. All cases of colorectal cancers histologically con- firmed were included. The Astler and Coller classification was used to classify lesions by level of extension. Results: 225 patients were included with a sex ratio (M/F) of 1.39, an average age of 52.3 years. Location of the lesion was rectal (37.7%) and colo- nic (62.3%). Clinical manifestations were dominated by rectal bleeding (26.9%), oc- clusive syndrome (16.5%) and transit disorders (11.6%). Endoscopic lesions were of stenosing (45.2%), ulcero-burgeoning (39%), ulcerous (7.5%) and burgeoning (4.7%) types. Histological profiles were adenocarcinoma (88.9%), carcinoma (3.1%) and lymphoma (2.6%). The work-up for extension revealed metastasis in 33.6% of cases. These were stage B (49%) and C (36%) among the 95 cancers that received the Astler and Coller classification. The treatment was curative (80.83%) and palliative (19.16%). Conclusion: Colorectal cancer is a reality in Africa. However, its diagnosis still re- mains delayed, which increases the prognosis, hence the need to promote screening tests.

Auteur(s) : A. Sarr, A. H. Isselmou, E. A. M. Horma Babana, D. Diédhiou, A. Horma Babana, M. Ndour Mbaye, D. Sow, S. N. Diop
Pages : 139-146
Année de publication : 2016
Revue : Open Journal of Internal Medicine
N° de volume : 6,
Type : Article
Mise en ligne par : NDOUR Ndèye Maïmouna