Accueil > Résultats de la recherche > Suite de la publication

First total synthesis of (4R,5R,11S) and (4R,5R,11R)-iso- cladospolide B

The two enantiomers of natural products (4S, 5S, 11R)-and (4S, 5S, 11S)-iso-cladospolide B have been synthesized and their structures unambiguously confirmed by X-ray crystallographic analysis. Key steps of the synthesis include the use of tri-O-acetyl-D-glucal as precursor for a chiral furan diol which, after side chain transformation, underwent singlet oxygen oxidation to afford the target butenolides.


Auteur(s) : María González, Zoila Gándara, Matar Seck, Generosa Gómez1 and Yagamare Fall
Pages : 18-29
Année de publication : 2015
Revue : Mediterranean Journal of Chemistry
N° de volume : 4(1)
Type : Article
Statut Editorial : ISI (International Scientific Indexing)
Mise en ligne par : SECK Matar