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Evolution of biochemical parameters in Senegalese women using hormonal contraceptive

This study was conducted to assess the effects of hormonal contraceptives in biochemistry parameters, in two family planning clinics and Medical laboratory of Biochemistry, University Cheikh Anta Diop of Dakar (UCAD). This study has involved159 women of childbearing age in which 106 are hormonal contraception users and 53 women are non users, with the average pregnancy of 3. They had a mean age of 27 +/- 7 years, and a mean weight of 65.25 +/- 10.8. Each participant was submitted to a gynecological examination and blood samples were measured by a biochemistry RA-XT (Technikon ®) autoanalyzer. After six months, we observed in women users a statistically significant increase in uric acid level. We also observed an increase in AST, ALT and PAL levels according to contraceptives used. The significant decrease in urea and lipid such as triglycerides, high density lipoprotein cholesterol (CHDL) and total cholesterol (CT) was observed within the reference range. Other parameters explored remain unchanged.


Auteur(s) : Diallo-Agne F, Cissé F, Ndiaye A, Doupa D, Gueye C, Diatta A, Sarr Nd. G, Sall N D, Cissé C.T, Touré M.
Pages : 20-25
Année de publication : 2013
Revue : International Research Journal of Biochemistry and Bioinformatics
N° de volume : 3
Type : Article
Statut Editorial : Full Length Research Paper
Mise en ligne par : CISSE Fatou